Examining the Starting Dose of Glyburide in Gestational Diabetes
نویسندگان
چکیده
منابع مشابه
Glyburide for the treatment of gestational diabetes. A critical appraisal.
The clinical experience with glyburide treatment of GDM has moved ahead of the science. A single randomized controlled trial of glyburide versus insulin indicates that glyburide treatment can provide a relatively safe alternative to insulin therapy. Subsequent retrospective trials have shown that up to 20% of GDM patients, especially those with substantial pretreatment hyperglycemia, are likely...
متن کاملReview of metformin and glyburide in the management of gestational diabetes
BACKGROUND Worldwide, gestational diabetes affects 15% of pregnancies. It is recommended in patients with gestational diabetes to initiate diet therapy and if this is not adequate, insulin is the next treatment modality. While insulin is the preferred drug therapy to manage gestational diabetes in the majority of women, it may not always be the best option for all women. OBJECTIVE The purpose...
متن کاملComparison of glyburide and insulin in the management of gestational diabetes: A meta-analysis
OBJECTIVE The aim of this meta-analysis was to determine the efficacy and safety of glyburide as a treatment for gestational diabetes mellitus (GDM) compared to insulin. METHODS A meta-analysis was conducted to compare the management of gestational diabetes with glyburide and insulin. Studies fulfilling all of the following inclusion criteria were included in this meta-analysis: subjects were...
متن کاملPerinatal impact of the use of metformin and glyburide for the treatment of gestational diabetes mellitus.
OBJECTIVE To evaluate the perinatal impact of metformin and glyburide in the treatment of gestational diabetes mellitus (GDM). METHODS A randomized clinical trial conducted from July 2008 until September 2010 studied 200 pregnant women with GDM who required adjunctive therapy to diet and physical activity. Patients were randomized to use metformin (n=104) or glyburide (n=96). The drugs were r...
متن کاملAssociation of Adverse Pregnancy Outcomes With Glyburide vs Insulin in Women With Gestational Diabetes.
IMPORTANCE Glyburide is thought to be safe for use during pregnancy for treatment of gestational diabetes mellitus (GDM). However, there are limited data on the effectiveness of glyburide when compared with insulin as used in a real-world setting. OBJECTIVE To estimate the risk of adverse maternal and neonatal outcomes in women with GDM treated with glyburide compared with insulin. DESIGN, ...
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ژورنال
عنوان ژورنال: American Journal of Perinatology
سال: 2015
ISSN: 0735-1631,1098-8785
DOI: 10.1055/s-0035-1564063